Salbutamol
Product Specifications
UNSPSC Description
Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD)[1][2].
Target Antigen
Adrenergic Receptor; ERK
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway;Neuronal Signaling;Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Salbutamol.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(CNC(C)(C)C)C1=CC=C(O)C(CO)=C1
Molecular Weight
239.31
References & Citations
[1]Lu Y, et al. Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. J Cancer. 2022 Jan 1;13(2):401-412.|[2]Hong YP, et al. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47(6):436-445.Adv Sci (Weinh). 2024 Sep 4:e2402393.|Respir Res. 2022 Dec 28;23(1):380.|Cell Rep. 2019 Dec 3;29(10):2929-2935.e4|Eur J Med Chem. 2024 Dec 5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1037/Salbutamol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1037/Salbutamol-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
18559-94-9
Available Sizes
Curated Selection
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