Salbutamol

Salbutamol (Albuterol) is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease[1][2].

Product Specifications

CAS Number

[18559-94-9]

Product Name Alternative

Albuterol; AH-3365

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor; ERK

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway; Neuronal Signaling; Stem Cell/Wnt

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Salbutamol.html

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(CNC(C)(C)C)C1=CC=C(O)C(CO)=C1

Molecular Formula

C13H21NO3

Molecular Weight

239.31

Precautions

H302, H315, H319, H335

References & Citations

[1]Lu Y, et al. Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. J Cancer. 2022 Jan 1;13 (2) :401-412.|[2]Hong YP, et al. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47 (6) :436-445.