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Boc-dPhe-Leu-dPhe-Leu-Phe

Boc-dPhe-Leu-dPhe-Leu-Phe (Boc-fLfLF) is a selective N-formyl peptide receptor1 (FPR1) antagonist. Boc-dPhe-Leu-dPhe-Leu-Phe inhibits fMIFL -induced NADPH oxidase activity. Boc-dPhe-Leu-dPhe-Leu-Phe can be used for the study of inflammation[1].

Product Specifications

CAS Number

148182-34-7

UNSPSC

12352209

Target

Formyl Peptide Receptor (FPR)

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/n-boc-phe-leu-phe-leu-phe.html

Purity

98.91

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

CC(C)(C)OC(N[C@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)CC3=CC=CC=C3)=O)=O)=O

Molecular Formula

C44H59N5O8

Molecular Weight

785.97

References & Citations

[1]Skovbakke SL, et al. The peptidomimetic Lau- (Lys-βNSpe) 6-NH2 antagonizes formyl peptide receptor 2 expressed in mouse neutrophils. Biochem Pharmacol. 2016 Nov 1;119:56-65.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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