Human CDK1 Protein

<strong>Human CDK1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011904_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Cyclin-dependent kinase 1 isoform 1 protein, CDC2 protein, CDC28A protein, P34CDC2 protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Haneke K, Schott J, Lindner D, Hollensen AK, Damgaard CK, Mongis C, Knop M, Palm W, Ruggieri A, Stoecklin G. CDK1 couples proliferation with protein synthesis J Cell Biol. 2020 Mar 2;219(3):e201906147._x000D_ 2: Yu J, Raia P, Ghent CM, Raisch T, Sadian Y, Cavadini S, Sabale PM, Barford D, Raunser S, Morgan DO, Boland A. Structural basis of human separase regulation by securin and CDK1-cyclin B1 Nature. 2021 Aug;596(7870):138-142._x000D_ 3: Xie B, Wang S, Jiang N, Li JJ. Cyclin B1/CDK1-regulated mitochondrial bioenergetics in cell cycle progression and tumor resistance Cancer Lett. 2019 Feb 28;443:56-66._x000D_ 4: Schmidt M, Rohe A, Platzer C, Najjar A, Erdmann F, Sippl W. Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases Molecules. 2017 Nov 23;22(12):2045._x000D_ 5: Li Q, Zhou D, Jia F, Zhang L, Ashraf U, Li Y, Duan H, Song Y, Chen H, Cao S, Ye J. Japanese Encephalitis Virus NS1' Protein Interacts with Host CDK1 Protein to Regulate Antiviral Response Microbiol Spectr. 2021 Dec 22;9(3):e0166121._x000D_ 6: Singh P, Pesenti ME, Maffini S, Carmignani S, Hedtfeld M, Petrovic A, Srinivasamani A, Bange T, Musacchio A. BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis Mol Cell. 2021 Jan 7;81(1):67-87.e9._x000D_ 7: Wu CX, Wang XQ, Chok SH, Man K, Tsang SHY, Chan ACY, Ma KW, Xia W, Cheung TT. Blocking CDK1/PDK1/β-Catenin signaling by CDK1 inhibitor RO3306 increased the efficacy of sorafenib treatment by targeting cancer stem cells in a preclinical model of hepatocellular carcinoma Theranostics. 2018 Jun 13;8(14):3737-3750._x000D_ 8: Zhang P, Kawakami H, Liu W, Zeng X, Strebhardt K, Tao K, Huang S, Sinicrope FA. Targeting CDK1 and MEK/ERK Overcomes Apoptotic Resistance in BRAF-Mutant Human Colorectal Cancer Mol Cancer Res. 2018 Mar;16(3):378-389._x000D_ 9: Crncec A, Hochegger H. Triggering mitosis FEBS Lett. 2019 Oct;593(20):2868-2888._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/33896262">10: Xing Z, Wang X, Liu J, Zhang M, Feng K, Wang X. Expression and prognostic value of CDK1, CCNA2, and CCNB1 gene clusters in human breast cancer J Int Med Res. 2021 Apr;49(4):300060520980647. </a>_x000D_ _x000D_ <strong>Products Related to Human CDK1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>