Rabbit anti Human KLF14

Product Specifications

Background

KLF14 is a member of the KrŸppel-like factor family of transcription factors. It regulates the transcription of various genes, including TGF RII (the type II receptor for TGF ). KLF14 is expressed in many tissues, lacks introns, and is subject to parent-specific expression.

CAS Number

9007-83-4

Synonyms

Krueppel-like factor 14, BTE-Binding Protein 5

UniProt

Q8TD94

Host

Rabbit

Species Reactivity

Human

Isotype

IgG

Conjugation

Affinity Purified

Type

Antigen Immunoaffinity Purified Polyclonal

Applications

WB, IHC

Purification Method

Antigen Immunoaffiinity Purification

Assay Principle

Antibody can be used for immunohistochemistry (2-4 µg/mL) and Western blotting (1-2 µg/mL). Optimal concentration should be evaluated by serial dilutions.

Stability

See expiration date on vial

Concentration

See vial for Concentration

Form

Provided as solution in phosphate buffered saline with 0,08% sodium azide

Precautions

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.

References & Citations

1. Truty, M.J., et al. ‘Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling.’ J. Biol. Chem., 284, 6291-6300 (2009) 2. Swamynathan, S.K. ‘Krüppel-like factors: three fingers in control.’ Hum. Genomics, 4, 263-270 (2010) 3. Parker-Katiraee, L., et al. ‘Identification of the imprinted KLF14 transcription factor undergoing Human-specific accelerated evolution.’ PLoS Genet., 3, e65, (2007)