KJ Pyr 9
KJ Pyr 9 is an inhibitor of MYC with a Kd of 6.5 nM in in vitro assay.
Product Specifications
CAS Number
581073-80-5
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Autophagy; c-Myc
Type
Reference compound
Related Pathways
Apoptosis; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/KJ-Pyr-9.html
Purity
99.62
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(N)C1=CC=C(C2=CC(C3=CC=CO3)=NC(C4=CC=C([N+]([O-])=O)C=C4)=C2)C=C1
Molecular Formula
C22H15N3O4
Molecular Weight
385.37
Precautions
H315, H319, H320
References & Citations
[1]Hart JR, et al. Inhibitor of MYC identified in a Kröhnke pyridine library. Proc Natl Acad Sci U S A. 2014 Aug 26;111 (34) :12556-61.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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