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KJ Pyr 9

KJ Pyr 9 is an inhibitor of MYC with a Kd of 6.5 nM in in vitro assay.

Product Specifications

CAS Number

581073-80-5

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Autophagy; c-Myc

Type

Reference compound

Related Pathways

Apoptosis; Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/KJ-Pyr-9.html

Purity

99.62

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N)C1=CC=C(C2=CC(C3=CC=CO3)=NC(C4=CC=C([N+]([O-])=O)C=C4)=C2)C=C1

Molecular Formula

C22H15N3O4

Molecular Weight

385.37

Precautions

H315, H319, H320

References & Citations

[1]Hart JR, et al. Inhibitor of MYC identified in a Kröhnke pyridine library. Proc Natl Acad Sci U S A. 2014 Aug 26;111 (34) :12556-61.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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