Tyloxapol (Highly Pure)

<strong>Tyloxapol (Highly Pure)</strong>_x000D_ <strong>Catalog number:</strong> B2017714_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 g_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> RT_x000D_ <strong>Keywords:</strong> 4-(1,1,3,3-Tetramethylbutyl)phenol polymer with formaldehyde and oxirane_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Guo W, Li H, Lou Y, Zhang Y, Wang J, Qian M, Wei H, Xiao J, Xu Y. Tyloxapol inhibits RANKL-stimulated osteoclastogenesis and ovariectomized-induced bone loss by restraining NF-κB and MAPK activation J Orthop Translat. 2021 Apr 10;28:148-158._x000D_ 2: Jin M, Zhang D, Zheng L, Wei Y, Yan S, Qin H, Wang Q, Zhao L, Feng H. Lipopolysaccharide and tyloxapol accelerate the development of atherosclerosis in mice Lipids. 2022 Mar;57(2):83-90._x000D_ 3: Kuo JH, Jan MS, Chiu HW. Cytotoxic properties of tyloxapol Pharm Res. 2006 Jul;23(7):1509-16._x000D_ 4: Ji X, Ma Q, Wang X, Ming H, Bao G, Fu M, Wei C. Digeda-4 decoction and its disassembled prescriptions improve dyslipidemia and apoptosis by regulating AMPK/SIRT1 pathway on tyloxapol-induced nonalcoholic fatty liver disease in mice J Ethnopharmacol. 2023 Dec 5;317:116827._x000D_ 5: Shen B, Wang Y, Cheng J, Peng Y, Zhang Q, Li Z, Zhao L, Deng X, Feng H. Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2 Phytomedicine. 2023 Jan;109:154561._x000D_ 6: Serikov VB, Glazanova TV, Jerome EH, Fleming NW, Higashimori H, Staub NC Sr. Tyloxapol attenuates the pathologic effects of endotoxin in rabbits and mortality following cecal ligation and puncture in rats by blockade of endotoxin receptor-ligand interactions Inflammation. 2003 Aug;27(4):175-90._x000D_ 7: Shen B, Feng H, Cheng J, Li Z, Jin M, Zhao L, Wang Q, Qin H, Liu G. Geniposide alleviates non-alcohol fatty liver disease via regulating Nrf2/AMPK/mTOR signalling pathways J Cell Mol Med. 2020 May;24(9):5097-5108._x000D_ 8: Kuo JH, Lin YL, Tseng JW. Interactions between U-937 human macrophages and tyloxapol Colloids Surf B Biointerfaces. 2008 Jul 15;64(2):208-15._x000D_ 9: Ghio AJ, Marshall BC, Diaz JL, Hasegawa T, Samuelson W, Povia D, Kennedy TP, Piantodosi CA. Tyloxapol inhibits NF-kappa B and cytokine release, scavenges HOCI, and reduces viscosity of cystic fibrosis sputum Am J Respir Crit Care Med. 1996 Sep;154(3 Pt 1):783-8._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/10533679">10: Sachs S, Ghio AJ, Young SL. Tyloxapol confers durable protection against hyperoxic lung injury in the rat Exp Lung Res. 1999 Sep;25(6):543-59. </a>_x000D_ _x000D_ <strong>Products Related to Tyloxapol (Highly Pure) can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>