Cefazolin-13C2,15N (sodium)
Cefazolin-13C2,15N (sodium) is 13C and 15N labeled Cefazolin (sodium) . Cefazolin sodium is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research[1][2][3]. Cefazolin sodium has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD) .
Product Specifications
CAS Number
1346602-30-9
UNSPSC
12352005
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds
Type
Reference compound
Related Pathways
Anti-infection; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cefazolin-13c2-15n-sodium.html
Smiles
O=C1[C@@](N[13C]([13CH2][15N]2N=NN=C2)=O)([C@]3(SCC(CSC4=NN=C(S4)C)=C(N31)C([O-])=O)[H])[H].[Na+]
Molecular Formula
C12 13C2H13N7 15NNaO4S3
Molecular Weight
479.47
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]R Quintiliani, et al. Cefazolin. Ann Intern Med. 1978 Nov;89 (5 Pt 1) :650-6.|[3]Peng Liang, et al. Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice. J Neuroinflammation. 2018 Aug 22;15 (1) :235.|[4]Barbara Żyżyńska-Granica, et al. The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor. Sci Rep. 2020 Feb 19;10 (1) :2886.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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