Isoferulic acid

Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes[1][2][3][4].

Product Specifications

CAS Number

[537-73-5]

Product Name Alternative

3-Hydroxy-4-methoxycinnamic acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor; Influenza Virus

Type

Natural Products

Related Pathways

Anti-infection; GPCR/G Protein; Neuronal Signaling

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Infection; Endocrinology; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/3-Hydroxy-4-methoxycinnamic_acid.html

Concentration

10mM

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C/C1=CC=C(OC)C(O)=C1

Molecular Formula

C10H10O4

Molecular Weight

194.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Liu IM, et al. Mediation of beta-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther. 2003 Dec;307 (3) :1196-204.|[2]Sakai S, et al. Administration of isoferulic acid improved the survival rate of lethal influenza virus pneumonia in mice. Mediators Inflamm. 2001 Apr;10 (2) :93-6.|[3]Meeprom A, et al. Isoferulic acid, a new anti-glycation agent, inhibits fructose- and glucose-mediated protein glycation in vitro. Molecules. 2013 May 30;18 (6) :6439-54.|[4]Wang X, et al. Evaluation of antioxidant activity of isoferulic acid in vitro. Nat Prod Commun. 2011 Sep;6 (9) :1285-8.