Fludarabine-Cl

Fludarabine-Cl has an inhibitory effect on RNA adenosine deaminase 1 (ADAR1) with an IC50 of 0.87 μM and can be used to prevent and/or study cancer or tumor-related diseases[1].

Product Specifications

CAS Number

[2734853-80-4]

UNSPSC

12352005

Target

Adenosine Deaminase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fludarabine-cl.html

Concentration

10mM

Purity

99.71

Solubility

H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

NC1=C2C(N([C@]3([H])O[C@@H]([C@H]([C@H]3O)O)CCl)C=N2)=NC(F)=N1

Molecular Formula

C10H11ClFN5O3

Molecular Weight

303.68

References & Citations

[1]Polysubstituted purine compound and preparation method and application thereof. CN113549076A.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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