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δ opioid receptor antagonist 1

δ opioid receptor antagonist 1 (compound 6-Cy3) is a fluorescent antagonist probe with high selectivity for δ opioid receptor (DOR) (Ki=1.7 nM) . δ opioid receptor antagonist 1 can be used to study the mechanism of pain perception[1].

Product Specifications

UNSPSC

12171500

Target

Fluorescent Dye; Opioid Receptor

Type

Dye Reagents

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/δ-opioid-receptor-antagonist-1.html

Smiles

OC1=C2O[C@@H]3[C@@]4(C2=C(C[C@@H]5[C@@]4(CC6=C3NC7=C6C=CC=C7NC(CNC(CNC(CNC(CNC(CCCCC[N+]8=C(C(C)(C9=C8C=CC(S(=O)([O-])=O)=C9)C)/C=C/C=C%10N(C%11=C(C/%10(C)C)C=C(S(=O)(O)=O)C=C%11)C)=O)=O)=O)=O)=O)O)C=C1)CCN5CC%12CC%12

Molecular Formula

C64H73N9O14S2

Molecular Weight

1256.45

References & Citations

[1]Drakopoulos, et al. "Design, Synthesis, and Characterization of New δ Opioid Receptor-Selective Fluorescent Probes and Applications in Single-Molecule Microscopy of Wild-Type Receptors." Journal of Medicinal Chemistry (2024) .

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Isoform

δ Opioid Receptor/DOR

Frequently Asked Questions

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