FSL-1

FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection[1][2].

Product Specifications

CAS Number

[322455-70-9]

UNSPSC

12352209

Target

Antibiotic; Toll-like Receptor (TLR)

Type

Peptides

Related Pathways

Anti-infection; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fsl-1.html

Purity

99.22

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

O=C([C@H]1N(CCC1)C([C@H](CC(O)=O)NC(CNC([C@@H](N)CSCC(COC(CCCCCCCCCCCCCCC)=O)OC(CCCCCCCCCCCCCCC)=O)=O)=O)=O)N[C@@H](CCCCN)C(N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O

Molecular Formula

C84H140N14O18S

Molecular Weight

1666.16

References & Citations

[1]Rasheed Ahmad, et al. FSL-1 induces MMP-9 production through TLR-2 and NF-κB /AP-1 signaling pathways in monocytic THP-1 cells. Cell Physiol Biochem. 2014;34 (3) :929-42.|[2]William A Rose 2nd, et al. FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection. Virol J. 2009 Nov 10;6:195.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

TLR2; TLR6

Citation 01

Int J Med Sci. 2022 Mar 21;19 (4) :631-639.|Adv Sci (Weinh) . 2025 Sep 26:e02395.|Food Res Int. 2022 Dec;162 (Pt A) :112029.|J Ethnopharmacol. 2024 May 10:325:117824.