Palm11-PrRP31
Palm11-PrRP31 is a lipidized endogenous appetite inhibitory neuropeptide (PrRP) analogue. palm11-PrRP31 is GPR10 (EC50=39 pM) and NPFF-R2 effective dual agonists. palm11-PrRP31 is able to mimic the natural function of PrRP by binding to these receptors to reduce food intake. palm11-PrRP31 can be used as a potential anti-obesity agent and for the study of neuropeptide-receptor interaction[1].
Product Specifications
UNSPSC
12352209
Target
Neuropeptide FF Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/palm11-prrp31.html
Smiles
O=C(CC[C@H](NC(CCCCCCCCCCCCCCC)=O)C(O)=O)NCCCC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CO)=O)CCCNC(N)=N)=O)[C@@H](C)O)=O)CC1=CNC=N1)=O)CCCNC(N)=N)=O)CC2=CNC=N2)=O)CO)=O)CCSC)=O)CCC(O)=O)=O)[C@H](CC)C)=O)C(N[C@H](C(N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N5[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N)=O)CC6=CC=CC=C6)=O)CCCNC(N)=N)=O)=O)C(C)C)=O)CCC5)=O)CCCNC(N)=N)=O)[C@H](CC)C)=O)=O)CCCNC(N)=N)=O)CO)=O)C)=O)CC7=CC=C(O)C=C7)=O)CC8=CNC9=CC=CC=C89)=O)C)=O)CCC4)=O)CC(N)=O)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC3)=O)[C@@H](C)O)=O
Molecular Formula
C181H289N55O46S
Molecular Weight
4003.64
References & Citations
[1]Strnadová V, et al. Search for lipidized PrRP analogs with strong anorexigenic effect: in vitro and in vivo studies[J]. Neuropeptides, 2023, 98: 102319.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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