Acepromazine-OTs

Acepromazine-OTs is a TRIM21 ligand used in the recruitment of the TRIM21 protein. Acepromazine-OTs can be connected to the target protein ligand through a linker to form a PROTAC molecule, TrimTAC1 (HY-169355) [1].

Product Specifications

CAS Number

[102951-20-2]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/acepromazine-ots.html

Smiles

CC(C1=CC2=C(C=C1)SC3=C(C=CC=C3)N2CCCOS(C4=CC=C(C=C4)C)(=O)=O)=O

Molecular Formula

C24H23NO4S2

Molecular Weight

453.57

References & Citations

[1]Panrui Lu, et al. Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell. 2024 Oct 30:S0092-8674 (24) 01197-8.