Acepromazine-OTs
Acepromazine-OTs is a TRIM21 ligand used in the recruitment of the TRIM21 protein. Acepromazine-OTs can be connected to the target protein ligand through a linker to form a PROTAC molecule, TrimTAC1 (HY-169355) [1].
Product Specifications
CAS Number
[102951-20-2]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/acepromazine-ots.html
Smiles
CC(C1=CC2=C(C=C1)SC3=C(C=CC=C3)N2CCCOS(C4=CC=C(C=C4)C)(=O)=O)=O
Molecular Formula
C24H23NO4S2
Molecular Weight
453.57
References & Citations
[1]Panrui Lu, et al. Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell. 2024 Oct 30:S0092-8674 (24) 01197-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRIM21
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