RNase H2
RNase H2 is the predominant source of RNase H activity in mammalian and human cells. RNase H2 protects genome integrity. RNase H2 has been associated with ribonucleotide removal from genomic DNA in yeast and mouse, where it is required for embryonic development[1][2].
Product Specifications
UNSPSC
12352204
Target
Others
Type
Enzyme
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rnase-h2.html
Purity
96
Solubility
10 mM in DMSO
Smiles
[RNaseH2]
References & Citations
[1]Feng S, Cao Z. Is the role of human RNase H2 restricted to its enzyme activity? Prog Biophys Mol Biol. 2016 May;121 (1) :66-73.|[2]Chon H, et al. RNase H2 roles in genome integrity revealed by unlinking its activities. Nucleic Acids Res. 2013 Mar 1;41 (5) :3130-43.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
Frequently Asked Questions
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