Vilaprisan
Vilaprisan is a selective progesterone receptor modulator (SPRM), which targets progesterone receptors. Vilaprisan can inhibit cell proliferation and stimulate apoptosis. Vilaprisan has oral efficacy and anti-proliferative activity against uterine leiomyoma (UF[1]) .
Product Specifications
CAS Number
1262108-14-4
Product Name Alternative
BAY 1002670
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Progesterone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vilaprisan.html
Purity
99.75
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@](CC[C@@]2(O)C(F)(F)C(F)(F)F)([H])[C@@]3([H])C([C@@H](C4=CC=C(C=C4)S(C)(=O)=O)C1)=C5C(CC3)=CC(CC5)=O
Molecular Formula
C27H29F5O4S
Molecular Weight
544.57
Precautions
H302, H315, H319, H335
References & Citations
[1]Schultze-Mosgau MH, et al. Pharmacokinetics and safety of the selective progesterone receptor modulator vilaprisan in healthy postmenopausal women
. Int J Clin Pharmacol Ther. 2017 Jan;55 (1) :16-24.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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