Vilaprisan

Vilaprisan is a selective progesterone receptor modulator (SPRM), which targets progesterone receptors. Vilaprisan can inhibit cell proliferation and stimulate apoptosis. Vilaprisan has oral efficacy and anti-proliferative activity against uterine leiomyoma (UF[1]) .

Product Specifications

CAS Number

[1262108-14-4]

Product Name Alternative

BAY 1002670

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Progesterone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vilaprisan.html

Purity

99.75

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@](CC[C@@]2(O)C(F)(F)C(F)(F)F)([H])[C@@]3([H])C([C@@H](C4=CC=C(C=C4)S(C)(=O)=O)C1)=C5C(CC3)=CC(CC5)=O

Molecular Formula

C27H29F5O4S

Molecular Weight

544.57

Precautions

H302, H315, H319, H335

References & Citations

[1]Schultze-Mosgau MH, et al. Pharmacokinetics and safety of the selective progesterone receptor modulator vilaprisan in healthy postmenopausal women . Int J Clin Pharmacol Ther. 2017 Jan;55 (1) :16-24.