Influenza A virus-IN-14
Influenza A virus-IN-14 (Compound 37) is an inhibitor for influenza virus type A (IAV), which inhibits H1N1 with an EC50 of 23 nM. Influenza A virus-IN-14 exhibits low cytotoxicity with CC50 of more than 100 μM. Influenza A virus-IN-14 inhibits cytopathic effect and improves the survival rates of cell Calu3. Influenza A virus-IN-14 exhibits synergistic activity with the neuraminidase inhibitor Oseltamivir. Influenza A virus-IN-14 exhibits poor pharmacokinetic properties in CD-1 mouse[1].
Product Specifications
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/influenza-a-virus-in-14.html
Smiles
CO/N=C(C1(CNC2=O)CCC1)\CCCOC(C(CC3=C2C=CC(C(F)(F)F)=C3)=C)=O
Molecular Formula
C22H25F3N2O4
Molecular Weight
438.44
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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