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Laninamivir (TFA)

Laninamivir TFA (R 125489 TFA) is an antiviral compound with inhibitory and prophylactic activity against influenza A and B viruses. Laninamivir TFA is a long-acting neuraminidase inhibitor administered by nasal inhalation. Laninamivir TFA has shown good safety and efficacy in the inhibition of influenza viruses[1].

Product Specifications

CAS Number

[203120-18-7]

Product Name Alternative

R 125489 (TFA)

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/laninamivir-tfa.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H](O)[C@H]([C@@]1([H])[C@@H]([C@H](C=C(C(O)=O)O1)NC(N)=N)NC(C)=O)OC.OC(C(F)(F)F)=O

Molecular Formula

C15H23F3N4O9

Molecular Weight

460.36

References & Citations

[1]Vavricka CJ, et al. Structural and functional analysis of laninamivir and its octanoate prodrug reveals group specific mechanisms for influenza NA inhibition. PLoS Pathog. 2011 Oct;7 (10) :e1002249.|[2]Antiviral Drugs in Influenza

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Curated Selection

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