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Malachite green (hemioxalate) (Standard)

Malachite green hemioxalate (Standard) is the analytical standard of Malachite green hemioxalate. This product is intended for research and analytical applications. Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antimicrobial activity, which is attributed to inhibition of intracellular enzymes, intercalation into DNA, and/or interaction with cellular membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo.

Product Specifications

CAS Number

2437-29-8

Product Name Alternative

MCCK1 (Standard)

UNSPSC

12352211

Target

Apoptosis; Fungal; IKK; NF-κB; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Apoptosis; NF-κB; Others

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/malachite-green-hemioxalate-standard.html

Smiles

C/[N+](C)=C1C=C/C(C=C/1)=C(C2=CC=C(N(C)C)C=C2)\C3=CC=CC=C3.O=C(O)C([O-])=O.O=C(O)C(O)=O.[1/2]

Molecular Formula

C23H25N2.1/2C2H2O4.C2HO4

Molecular Weight

463.50

References & Citations

[1]Liu T, et, al. Identification of an IKBKE inhibitor with antitumor activity in cancer cells overexpressing IKBKE. Cytokine. 2019 Apr; 116: 78-87.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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