Malachite green (hemioxalate) (Standard)
Malachite green hemioxalate (Standard) is the analytical standard of Malachite green hemioxalate. This product is intended for research and analytical applications. Malachite green hemioxalate is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antimicrobial activity, which is attributed to inhibition of intracellular enzymes, intercalation into DNA, and/or interaction with cellular membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IκBα, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo.
Product Specifications
CAS Number
2437-29-8
Product Name Alternative
MCCK1 (Standard)
UNSPSC
12352211
Target
Apoptosis; Fungal; IKK; NF-κB; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Apoptosis; NF-κB; Others
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/malachite-green-hemioxalate-standard.html
Smiles
C/[N+](C)=C1C=C/C(C=C/1)=C(C2=CC=C(N(C)C)C=C2)\C3=CC=CC=C3.O=C(O)C([O-])=O.O=C(O)C(O)=O.[1/2]
Molecular Formula
C23H25N2.1/2C2H2O4.C2HO4
Molecular Weight
463.50
References & Citations
[1]Liu T, et, al. Identification of an IKBKE inhibitor with antitumor activity in cancer cells overexpressing IKBKE. Cytokine. 2019 Apr; 116: 78-87.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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