(2-Pyridyldithio) -PEG4-propargyl

(2-Pyridyldithio) -PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. (2-Pyridyldithio) -PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[2170240-99-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2-pyridyldithio-peg4-propargyl.html

Purity

98.47

Solubility

10 mM in DMSO

Smiles

C#CCOCCOCCOCCOCCSSC1=NC=CC=C1

Molecular Formula

C16H23NO4S2

Molecular Weight

357.49

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562