(2-Pyridyldithio) -PEG4-propargyl
(2-Pyridyldithio) -PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. (2-Pyridyldithio) -PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[2170240-99-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-pyridyldithio-peg4-propargyl.html
Purity
98.47
Solubility
10 mM in DMSO
Smiles
C#CCOCCOCCOCCOCCSSC1=NC=CC=C1
Molecular Formula
C16H23NO4S2
Molecular Weight
357.49
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
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