Unguinol
Unguinol is a depsidone originally isolated from A. unguis. It is an inhibitor of pyruvate phosphate dikinase (PPDK; IC50=42.3 μM) . It inhibits the growth of plants utilizing C4, but not C3, carbon fixation. Unguinol also inhibits the growth of the bacteria S. aureus and V. harveyi (GI50s=8.7 and 69.5 μM, respectively) and H460, MCF-7, and SF-268 cancer cells (GI50s=28.2, 50.8, and 44.3 μM, respectively) .
Product Specifications
CAS Number
[36587-59-4]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/unguinol.html
Smiles
CC1=C2C(OC3=C(C(O2)=O)C(C)=CC(O)=C3)=C(C=C1O)/C(C)=C/C
Molecular Formula
C19H18O5
Molecular Weight
326.34
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Stodola, et al. New depsidone from Aspergillus unguis. Phytochemistry 11 (6), 2107-2108 (1972) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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