Harringtonine
Harringtonine is a natural Cephalotaxus alkaloid that inhibits protein synthesis. Harringtonine has anti-chikungunya virus (CHIKV) activities with an EC50 of 0.24 μM.
Product Specifications
CAS Number
26833-85-2
UNSPSC
12352005
Hazard Statement
H300, H310, H330
Target
CHIKV; Influenza Virus
Type
Natural Products
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Harringtonine.html
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@](CC(OC)=O)(O)CCC(C)(O)C)O[C@H]1[C@](C2=CC(OCO3)=C3C=C2CCN4CCC5)([H])[C@]45C=C1OC
Molecular Formula
C28H37NO9
Molecular Weight
531.59
Precautions
H300, H310, H330
References & Citations
[1]Fresno M, et al. Inhibition of translation in eukaryotic systems by harringtonine. Eur J Biochem. 1977 Jan;72 (2) :323-30.|[2]Kaur P, et al. Inhibition of chikungunya virus replication by harringtonine, a novel antiviral that suppresses viral protein expression. Antimicrob Agents Chemother. 2013 Jan;57 (1) :155-67.|[3]Piao YF, et al. Growth inhibition of human myeloid leukemia cells in vitro by harringtonine. Gan To Kagaku Ryoho. 1990 Feb;17 (2) :281-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K3741303 1.0 µg DNA
Ppp1r14c sgRNA CRISPR Lentivector (Mouse) (Target 2)
Sign In for Pricing
View Details 
4030-8418 500 Tubes
DNA LoBind Tubes, DNA LoBind, 1.5 mL, PCR clean, colorless, 1 bag x 500 tubes
Sign In for Pricing
View Details