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N4-Benzoyl-7’-OH-N-trityl morpholino cytosine

Selected Variant

HY-W357201-01

Size: 100 mg

N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

125515-31-3

Product Name Alternative

N-[1- (6-Hydroxymethyl-4-trityl-morpholin-2-yl) -2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide

UNSPSC

12352005

Hazard Statement

H315-H319

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n4-benzoyl-7-oh-n-trityl-morpholino-cytosine.html

Solubility

10 mM in DMSO

Smiles

O=C(NC(C=CN1[C@H]2CN(C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C[C@@H](CO)O2)=NC1=O)C6=CC=CC=C6

Molecular Formula

C35H32N4O4

Molecular Weight

572.65

Precautions

P264-P280-P302+P352-P362+P364

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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