N4-Benzoyl-7’-OH-N-trityl morpholino cytosine
N4-Benzoyl-7’-OH-N-trityl morpholino cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[125515-31-3]
Product Name Alternative
N-[1- (6-Hydroxymethyl-4-trityl-morpholin-2-yl) -2-oxo-1,2-dihydro-pyrimidin-4-yl]-benzamide
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n4-benzoyl-7-oh-n-trityl-morpholino-cytosine.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C=CN1[C@H]2CN(C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C[C@@H](CO)O2)=NC1=O)C6=CC=CC=C6
Molecular Formula
C35H32N4O4
Molecular Weight
572.65
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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