Glutaminase

<strong>Glutaminase</strong> <strong>Catalog number:</strong> B2020190 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 1 kU <strong>Molecular Weight or Concentration:</strong> 58 kDa <strong>Supplied as:</strong> Lyophilized <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -20C <strong>Keywords:</strong> L-Glutamine amidohydrolase <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1: Ji C, Tang Y, Zhang Y, Li C, Liang H, Ding L, Xia X, Xiong L, Qi XR, Zheng JC. Microglial glutaminase 1 deficiency mitigates neuroinflammation associated depression Brain Behav Immun. 2022 Jan;99:231-245. 2: Masisi BK, El Ansari R, Alfarsi L, Rakha EA, Green AR, Craze ML. The role of glutaminase in cancer Histopathology. 2020 Mar;76(4):498-508. 3: Wu C, Chen L, Jin S, Li H. Glutaminase inhibitors: a patent review Expert Opin Ther Pat. 2018 Nov;28(11):823-835. 4: Ding L, Xu X, Li C, Wang Y, Xia X, Zheng JC. Glutaminase in microglia: A novel regulator of neuroinflammation Brain Behav Immun. 2021 Feb;92:139-156. 5: Dumontet C. Targeting glutaminase to starve lymphoma cells Haematologica. 2023 Jun 1;108(6):1468-1469. 6: Cyriac R, Lee K. Glutaminase inhibition as potential cancer therapeutics: current status and future applications J Enzyme Inhib Med Chem. 2024 Dec;39(1):2290911. 7: Chen Y, Tan L, Gao J, Lin C, Wu F, Li Y, Zhang J. Targeting glutaminase 1 (GLS1) by small molecules for anticancer therapeutics Eur J Med Chem. 2023 Apr 5;252:115306. 8: Ji C, Tang Y, Zhang Y, Huang X, Li C, Yang Y, Wu Q, Xia X, Cai Q, Qi XR, Zheng JC. Glutaminase 1 deficiency confined in forebrain neurons causes autism spectrum disorder-like behaviors Cell Rep. 2023 Jul 25;42(7):112712. 9: Adamoski D, M Dos Reis L, Mafra ACP, Corrêa-da-Silva F, Moraes-Vieira PMM, Berindan-Neagoe I, Calin GA, Dias SMG. HuR controls glutaminase RNA metabolism Nat Commun. 2024 Jul 4;15(1):5620. <a href="https://pubmed.ncbi.nlm.nih.gov/33446552">10: Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M. Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders Science. 2021 Jan 15;371(6526):265-270. </a> <br><strong>Products Related to Glutaminase can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>