Trypsin from Human Pancreas (High Activity)

<strong>Trypsin from Human Pancreas (High Activity)</strong>_x000D_ <strong>Catalog number:</strong> B2013381_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 vial_x000D_ <strong>Molecular Weight or Concentration:</strong> 1,000 BAEE units_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Trypsin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Whitcomb DC, Lowe ME. Human pancreatic digestive enzymes Dig Dis Sci. 2007 Jan;52(1):1-17._x000D_ 2: Saluja A, Dudeja V, Dawra R, Sah RP. Early Intra-Acinar Events in Pathogenesis of Pancreatitis Gastroenterology. 2019 May;156(7):1979-1993._x000D_ 3: Sahin-Tóth M. Human mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction Protein Pept Lett. 2005 Jul;12(5):457-64._x000D_ 4: Pubols MH, Bartelt DC, Greene LJ. Trypsin inhibitor from human pancreas and pancreatic juice J Biol Chem. 1974 Apr 10;249(7):2235-42._x000D_ 5: Suhaj P, Olejar T, Matej R. PAR2: The Cornerstone of Pancreatic Diseases Physiol Res. 2022 Nov 28;71(5):583-596._x000D_ 6: Weiss FU, Laemmerhirt F, Aghdassi A, Lerch MM. New horizons in pancreatic genetics Curr Opin Gastroenterol. 2020 Sep;36(5):437-442._x000D_ 7: Gui F, Zhang Y, Wan J, Zhan X, Yao Y, Li Y, Haddock AN, Shi J, Guo J, Chen J, Zhu X, Edenfield BH, Zhuang L, Hu C, Wang Y, Mukhopadhyay D, Radisky ES, Zhang L, Lugea A, Pandol SJ, Bi Y, Ji B. Trypsin activity governs increased susceptibility to pancreatitis in mice expressing human PRSS1R122H J Clin Invest. 2020 Jan 2;130(1):189-202._x000D_ 8: Fukushima K, Kamimura T, Takimoto-Kamimura M. Structure basis 1/2SLPI and porcine pancreas trypsin interaction J Synchrotron Radiat. 2013 Nov;20(Pt 6):943-7._x000D_ 9: Pesei ZG, Jancsó Z, Demcsák A, Németh BC, Vajda S, Sahin-Tóth M. Preclinical testing of dabigatran in trypsin-dependent pancreatitis JCI Insight. 2022 Nov 8;7(21):e161145._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/6803760">10: Anderson RA Jr, Beyler SA, Mack SR, Zaneveld LJ. Characterization of a high-molecular-weight form of human acrosin. Comparison with human pancreatic trypsin Biochem J. 1981 Nov 1;199(2):307-16. </a>_x000D_ _x000D_ <strong>Products Related to Trypsin from Human Pancreas (High Activity) can be found at</strong> <a href="https://moleculardepot.com/product-category/Enzymes/"> Enzymes</a>