Human BMP-13 Protein, His tag (Animal-Free)

Bone Morphogenetic Protein-13 (BMP-13), known as Growth differentiation factor 6 (GDF6), is an extracellular multifunctional cytokine that is also a member of the TGFβ family. BMP-13 can bind with the TGFβ receptor and induce SMAD protein signal transduction. BMP-13 is a regulatory protein that can affect the growth and differentiation of developing embryos. Moreover, it plays a role in regulating the patterning of the ectoderm and controlling eye development.

Product Specifications

Background

Product Name Alternative

Bone morphogenetic protein 13, subunit (CLMF p35), NK cell Stimulating Factor Chain 1, BMP13

Gene ID

392255

Accession Number

Q6KF10

Tag

BMP-13

Type

Cytokines and proteins

Applications

His tag

Purity

> 98 % as determined by SDS-PAGE

Activity

Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED₅₀ for this effect is 63-240 ng/mL.

Molecular Formula

14.50 kDa

Molecular Weight

14.50 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin :< 0.1 EU per 1 μg of the protein as determined by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA,10% FBS or 0.1%BSA) . Please prevent freeze-thaw cycles.

Protein Length

The recombinant Human BMP-13 consists of 121 amino acids and predicts a molecular mass of 14.5 kDa.

Formulation

Lyophilized from sterile 20mM sodium citrate,0.2 M NaCl, pH 3.5

Applications Notes

Human

Other Product Names

BMP13, BMP-13, BMP 13, bone morphogenetic protein 13, subunit (CLMF p35), NK cell Stimulating Factor Chain 1

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously.