HBV/HDV-IN-1

HBV/HDV-IN-1 (Compd 122) is a HBV, HDV and PD-1/PD-L1 inhibitor, with EC50 values of 8 nM for T cell activation and 35 nM for PD-L1 internalization[1].

Product Specifications

CAS Number

[3034161-55-9]

UNSPSC

12352005

Target

HBV; PD-1/PD-L1

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hbv-hdv-in-1.html

Smiles

O=C(NC1=CC=CC(C2=NC=CC(C3=NC(OC)=C(CNC[C@H](CC4)NC4=O)C=C3)=C2Cl)=C1Cl)C5=NC=C(CNC6CCN(C(C)=O)CC6)C(OC)=C5

Molecular Formula

C38H42Cl2N8O5

Molecular Weight

761.70

References & Citations

[1]Andrew G. Cole, et al. Substituted 1-arylaminocarbonyl-1'-heteroaryl compounds, substituted 1-heteroarylaminocarbonyl-1'-heteroaryl compounds and methods using same. Patent. WO2024069448A1.