TS-021 (free base)
DPP-IV-IN-1 is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV), a highly specific serine protease, with an IC50 of 4.6 nM.
Product Specifications
CAS Number
[625110-37-4]
Product Name Alternative
DPP-IV-IN-1
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ts-021-free-base.html
Concentration
10mM
Purity
98.84
Solubility
DMSO : 200 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#C[C@H]1N(C(CNC(C)(C)CO)=O)C[C@@H](F)C1
Molecular Formula
C11H18FN3O2
Molecular Weight
243.28
References & Citations
[1]Fukushima H, et al. Synthesis and structure-activity relationships of potent 4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors. Bioorg Med Chem. 2008 Apr 1;16 (7) :4093-106.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DPP-4
Available Sizes
Curated Selection
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