L-NMMA (hydrochloride)
L-NMMA (Tilarginine) hydrochloride competitively antagonizes L-arginine, and thus inhibits production of nitric oxide (NO) . L-NMMA hydrochloride is utilized as NO synthase antagonist in experimental settings[1].
Product Specifications
CAS Number
[156706-47-7]
Product Name Alternative
Tilarginine (hydrochloride) ; Methylarginine (hydrochloride)
UNSPSC
12352211
Hazard Statement
H302-H312-H332
Target
Endogenous Metabolite; NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/l-nmma-hydrochloride.html
Smiles
N[C@@H](CCCNC(NC)=N)C(O)=O.Cl
Molecular Formula
C7H17ClN4O2
Molecular Weight
224.69
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Frey C, et al., L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases. J Biol Chem. 1994 Oct 21;269 (42) :26083-91.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 4
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