L-NMMA (hydrochloride)

L-NMMA (Tilarginine) hydrochloride competitively antagonizes L-arginine, and thus inhibits production of nitric oxide (NO) . L-NMMA hydrochloride is utilized as NO synthase antagonist in experimental settings[1].

Product Specifications

CAS Number

[156706-47-7]

Product Name Alternative

Tilarginine (hydrochloride) ; Methylarginine (hydrochloride)

UNSPSC

12352211

Hazard Statement

H302-H312-H332

Target

Endogenous Metabolite; NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-nmma-hydrochloride.html

Smiles

N[C@@H](CCCNC(NC)=N)C(O)=O.Cl

Molecular Formula

C7H17ClN4O2

Molecular Weight

224.69

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

References & Citations

[1]Frey C, et al., L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthases. J Biol Chem. 1994 Oct 21;269 (42) :26083-91.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 4

Curated Selection

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