ASGR2/ASGPR2, Human (HEK293, His)

ASGR2 mediates endocytosis of desialylated glycoproteins, recognizing galactose and N-acetylgalactosamine units. Ligand binding leads to internalization and sorting organelle transport, followed by receptor return to the cell membrane. The receptor is suggested to function as a dimer. ASGR2 also interacts with LASS2. ASGR2/ASGPR2 Protein, Human (HEK293, His) is the recombinant human-derived ASGR2 protein, expressed by HEK293 , with N-His labeled tag.