DENND2B antibody
Product Specifications
Background
Guanine nucleotide exchange factor(GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.
Synonyms
DENN domain-containing protein 2B|HeLa tumor suppression 1|Suppression of tumorigenicity 5 protein|DENND2B|HTS1|ST5
Host
Rabbit
Reactivity
Human, Rat
Immunogen
suppression of tumorigenicity 5
Target
DENND2B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![TBC1D13 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2C5]](https://cdn.genprice.uk/genprice/genprice2.png)
TA505791AM 100 µL
TBC1D13 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2C5]
Ask
View Details