Mouse Cathepsin Z Protein

<strong>Mouse Cathepsin Z Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011701_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 500 µg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> fluorescent dye commonly used as a tracer agent_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> CTSZ protein, AI787083 protein, AU019819 protein, CTSX protein, D2Wsu143e protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Campden RI, Warren AL, Greene CJ, Chiriboga JA, Arnold CR, Aggarwal D, McKenna N, Sandall CF, MacDonald JA, Yates RM. Extracellular cathepsin Z signals through the α(5) integrin and augments NLRP3 inflammasome activation J Biol Chem. 2022 Jan;298(1):101459._x000D_ 2: Thygesen C, Ilkjær L, Kempf SJ, Hemdrup AL, von Linstow CU, Babcock AA, Darvesh S, Larsen MR, Finsen B. Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APP(SWE)/PS1(ΔE9) Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease Front Cell Neurosci. 2018 Nov 6;12:397._x000D_ 3: Allan ERO, Campden RI, Ewanchuk BW, Tailor P, Balce DR, McKenna NT, Greene CJ, Warren AL, Reinheckel T, Yates RM. A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis J Neuroinflammation. 2017 May 10;14(1):103._x000D_ 4: Deussing J, von Olshausen I, Peters C. Murine and human cathepsin Z: cDNA-cloning, characterization of the genes and chromosomal localization Biochim Biophys Acta. 2000 Apr 25;1491(1-3):93-106._x000D_ 5: Shen Y, Su Y, Silva FJ, Weller AH, Sostre-Colón J, Titchenell PM, Steger DJ, Seale P, Soccio RE. Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function Cell Rep. 2020 Mar 3;30(9):3079-3091.e5._x000D_ 6: Elhadad MA, Jonasson C, Huth C, Wilson R, Gieger C, Matias P, Grallert H, Graumann J, Gailus-Durner V, Rathmann W, von Toerne C, Hauck SM, Koenig W, Sinner MF, Oprea TI, Suhre K, Thorand B, Hveem K, Peters A, Waldenberger M. Deciphering the Plasma Proteome of Type 2 Diabetes Diabetes. 2020 Dec;69(12):2766-2778._x000D_ 7: Sevenich L, Schurigt U, Sachse K, Gajda M, Werner F, Müller S, Vasiljeva O, Schwinde A, Klemm N, Deussing J, Peters C, Reinheckel T. Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2497-502._x000D_ 8: Krueger S, Bernhardt A, Kalinski T, Baldensperger M, Zeh M, Teller A, Adolf D, Reinheckel T, Roessner A, Kuester D. Induction of premalignant host responses by cathepsin x/z-deficiency in Helicobacter pylori-infected mice PLoS One. 2013 Jul 30;8(7):e70242._x000D_ 9: Fang Y, Zhang D, Hu T, Zhao H, Zhao X, Lou Z, He Y, Qin W, Xia J, Zhang X, Ye LC. KMT2A histone methyltransferase contributes to colorectal cancer development by promoting cathepsin Z transcriptional activation Cancer Med. 2019 Jul;8(7):3544-3552._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26681805">10: Brandenstein L, Schweizer M, Sedlacik J, Fiehler J, Storch S. Lysosomal dysfunction and impaired autophagy in a novel mouse model deficient for the lysosomal membrane protein Cln7 Hum Mol Genet. 2016 Feb 15;25(4):777-91. </a>_x000D_ _x000D_ <strong>Products Related to Mouse Cathepsin Z Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>