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Human IL-4 Protein

Human Interleukin-4 (IL-4) is a cytokine that plays an important role in regulating inflammation and immune responses. It induces the differentiation of T cells to Th2 cells. This cytokine binds the IL-4 receptor that also binds another cytokine interleukin 13 (IL-13), which may explain the overlapping functions of IL-4 and IL-13.

Product Specifications

Background

Human Interleukin-4 (IL-4) is a cytokine that plays an important role in regulating inflammation and immuneresponses. It induces the differentiation of T cells to Th2 cells. This cytokine binds the IL-4 receptor that also binds another cytokine interleukin 13 (IL-13), which may explain the overlapping functions of IL-4 and IL-13.

Product Name Alternative

IL-4; Interleukin 4; BCGF1; BSF1

Gene ID

3565

Accession Number

P05112

Tag

IL-4

Type

Cytokines and proteins

Applications

No tag

Purity

> 98 % as determined by SDS-PAGE

Activity

Measured by its ability to induce proliferation in TF-1 cells. The ED50 for this effect is 0.5308 ng/mL.

Molecular Weight

15.1 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: <1 EU per 1 μg of the protein by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Lyophilized protein product should be stored desiccated below -20°C. The protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles

Protein Length

The recombinant Human IL-4 consists of 129 amino acids and predicts a molecular mass of 15.1 kDa.

Formulation

The protein was liquid in from sterile 20 mM Tris-HCl, 150mM NaCl, 10% glycerol, pH8.0. If you have any concerns or special requirements, please confirm with us.

Applications Notes

Human

Other Product Names

IL-4; Interleukin 4; BCGF1; BSF1

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously

Preparation

E. coli

Accession Number URL

https://www.uniprot.org/uniprotkb/P05112/entry

AA Sequence

Amino acid sequence derived from Human IL-4 (His25-Ser153) (P05112-1) was expressed.

Available Sizes

Curated Selection

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