Rhodblock 6
Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits phospho-MRLC (myosin regulatory light chain) localization[1].
Product Specifications
CAS Number
[886625-06-5]
UNSPSC
12352005
Hazard Statement
H302
Target
ROCK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rhodblock-6.html
Purity
98.94
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC2=C(C=C1)NN=C2)C3CCC3
Molecular Formula
C12H13N3O
Molecular Weight
215.25
Precautions
H302
References & Citations
[1]Adam B Castoreno, et al. Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. Nat Chem Biol. 2010 Jun;6 (6) :457-63.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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