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8 Hydroxy PIPAT (oxalate)

8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that promotes the release of histamine from enteric mast cells. 8 Hydroxy PIPAT oxalate activates serotonergic signaling pathways, leading to the degranulation of mast cells in both guinea pig and human intestinal preparations. 8 Hydroxy PIPAT oxalate enhances the spontaneous release of histamine, which may contribute to the regulation of gastrointestinal functions. 8 Hydroxy PIPAT oxalate has potential implications for understanding and treating functional gastrointestinal disorders such as irritable bowel syndrome.

Product Specifications

CAS Number

[1451210-48-2]

UNSPSC

12352005

Target

5-HT Receptor; Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/8-hydroxy-pipat-oxalate.html

Smiles

OC(C(O)=O)=O.OC1=C2C(CCC(C2)N(CCC)C/C=C/I)=CC=C1

Molecular Formula

C18H24INO5

Molecular Weight

461.29

References & Citations

[1]Mast cell expression of the serotonin1A receptor in guinea pig and human intestine

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT1 Receptor

Curated Selection

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