Amprolium (hydrochloride)
Amprolium hydrochloride is an anti-parasitic drug that's kind of taken orally, and it acts as an antagonist to thiamine in intestinal absorption[1][2][3][4].
Product Specifications
CAS Number
137-88-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Amprolium-hydrochloride.html
Purity
98.79
Solubility
H2O : ≥ 200 mg/mL
Smiles
CC1=CC=CC=[N+]1CC2=CN=C(CCC)N=C2N.[Cl-].Cl
Molecular Formula
C14H20Cl2N4
Molecular Weight
315.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Iqbal A, et al. Antiparasitic efficacy of Artemisia absinthium, toltrazuril and amprolium against intestinal coccidiosis in goats. J Parasit Dis. 2013 Apr;37 (1) :88-93.|[2]Lindsay DS, et al. Effects of sulfadiazine and amprolium on Neospora caninum (Protozoa: Apicomplexa) infections in mice. J Parasitol. 1990 Apr;76 (2) :177-9.|[3]Kennedy O Ogolla, et al. Efficacy of Sulphachloropyrazine, Amprolium Hydrochloride, Trimethoprim-Sulphamethoxazole, and Diclazuril against Experimental and Natural Rabbit Coccidiosis. J Vet Med. 2018 Oct 23:2018:5402469.|[4]G Rindi, et al. Action of Amprolium on the thiamine content of rat tissues. J Nutr. 1966 Jun;89 (2) :197-202.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Coccidia
Available Sizes
Frequently Asked Questions
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