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CBO-P11

CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling[1].

Product Specifications

CAS Number

612096-46-5

UNSPSC

12352209

Target

VEGFR

Type

Peptides

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cbo-p11.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@](NC([C@@H](NC([C@@H](NC(CNC([C@@H]1CCC(N)=O)=O)=O)CCC(N)=O)=O)CC2=CN=CN2)=O)([H])[C@@H](C)CC)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)CC3=CC=CC=C3)N4[C@@](C(N[C@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@@](C(N[C@H](C(N(CCC5)C5C(N[C@H](C(N1)=O)CC6=CN=CN6)=O)=O)CCCCN)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)CCSC)=O)([H])[C@@H](C)CC)=O)CCC(N)=O)=O)([H])CCC4

Molecular Formula

C94H145N29O25S

Molecular Weight

2113.40

References & Citations

[1]Stéphanie Deshayes, et al. "Click" conjugation of peptide on the surface of polymeric nanoparticles for targeting tumor angiogenesis. Pharm Res. 2011 Jul;28 (7) :1631-42.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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