CBO-P11
CBO-P11 specifically binds to receptor of VEGFR-2 and is used as targeting ligand for tumor angiogenesis. CBO-P11 is modified with a nearinfrared cyanine dye bearing an alkyne function, allowing both “click” coupling on azido-modified nanoparticles and fluorescence labelling[1].
Product Specifications
CAS Number
[612096-46-5]
UNSPSC
12352209
Target
VEGFR
Type
Peptides
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cbo-p11.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@](NC([C@@H](NC([C@@H](NC(CNC([C@@H]1CCC(N)=O)=O)=O)CCC(N)=O)=O)CC2=CN=CN2)=O)([H])[C@@H](C)CC)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)CC3=CC=CC=C3)N4[C@@](C(N[C@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@@](C(N[C@H](C(N(CCC5)C5C(N[C@H](C(N1)=O)CC6=CN=CN6)=O)=O)CCCCN)=O)([H])[C@@H](C)CC)=O)CCCNC(N)=N)=O)CCSC)=O)([H])[C@@H](C)CC)=O)CCC(N)=O)=O)([H])CCC4
Molecular Formula
C94H145N29O25S
Molecular Weight
2113.40
References & Citations
[1]Stéphanie Deshayes, et al. "Click" conjugation of peptide on the surface of polymeric nanoparticles for targeting tumor angiogenesis. Pharm Res. 2011 Jul;28 (7) :1631-42.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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