Human LIGHT / TNFSF14 Protein, Mouse IgG2a Fc Tag, low endotoxin
Tumor necrosis factor ligand superfamily member 14 (LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR) . LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.
Product Specifications
Background
Specifications
Accession Number
O43557-1
Expression Region
Asp 74 - Val 240
Host
HEK293
Target
LIGHT
Conjugation
Unconjugated
Tag
N-mFc (mIgG2a)
Source
Human
Stability
Endotoxin
0.01 EU per μg
Purity
95%
Bioactivity
Format
Powder
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Additives
Trehalose
Molecular Weight
45.1 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*2
Host or Source
HEK293
Species
Human
Protein ID
O43557-1
Preservative
Trehalose
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