HIV-1 integrase inhibitor 13
HIV-1 integrase inhibitor 13 (Compound 15) is an inhibitor for HIV-1 integrase with an IC50 of 1.8 nM. HIV-1 integrase inhibitor 13 inhibits the HIV-1 WT and HIV-1 T125A, with IC50 of 21 and 580 nM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
HIV Integrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-integrase-inhibitor-13.html
Smiles
OC(C(OC(C)(C)C)C1=C2C(CC[C@@]32CC[C@@H](C)CC3)=C(C=C1C)C(NC4CCCCCC4)=O)=O
Molecular Formula
C30H45NO4
Molecular Weight
483.68
References & Citations
[1]Adachi K, et al., Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety. Bioorg Med Chem Lett. 2024 Jun 26;110:129864.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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