Piperkadsin A
Piperkadsin A is a potent inhibitor of ROS. Piperkadsin inhibits PMA-induced ROS production in human polymorphonuclear neutrophils with an IC50 of 4.3 μM[1].
Product Specifications
CAS Number
895543-36-9
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/piperkadsin-a.html
Solubility
10 mM in DMSO
Smiles
COC(C=C1/C=C([C@]2(C(OC)=CC(C(CC=C)=C2)=O)OC)\C)=C(C=C1)O
Molecular Formula
C21H24O5
Molecular Weight
356.41
References & Citations
[1]Lin LC, et al. Anti-inflammatory neolignans from Piper kadsura. J Nat Prod. 2006 May;69 (5) :842-4.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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