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Piperkadsin A

Piperkadsin A is a potent inhibitor of ROS. Piperkadsin inhibits PMA-induced ROS production in human polymorphonuclear neutrophils with an IC50 of 4.3 μM[1].

Product Specifications

CAS Number

895543-36-9

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/piperkadsin-a.html

Solubility

10 mM in DMSO

Smiles

COC(C=C1/C=C([C@]2(C(OC)=CC(C(CC=C)=C2)=O)OC)\C)=C(C=C1)O

Molecular Formula

C21H24O5

Molecular Weight

356.41

References & Citations

[1]Lin LC, et al. Anti-inflammatory neolignans from Piper kadsura. J Nat Prod. 2006 May;69 (5) :842-4.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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