CrkL Recombinant Rabbit Monoclonal Antibody [JE50-21]
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CRKL
Swiss Prot
P46109 Human, P47941 Mouse, Q5U2U2 Rat
Cellular Locus
Cytosol, extrinsic component of postsynaptic membrane, neuromuscular junction, nucleoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human CrkL aa 254-303 / 303.
Isotype
IgG
Clone
JE50-21
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:200 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 34 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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