AZ-10417808
AZ-10417808 is a selective caspase-3 inhibitor. AZ-10417808 blocks apoptosis signaling pathway by inhibiting caspase-3 activity. AZ-10417808 can be used to study the effect of nicotine on plasmacytoid dendritic cell migration[1].
Product Specifications
CAS Number
331645-84-2
UNSPSC
12352005
Target
Apoptosis; Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/az-10417808.html
Smiles
O=C(C1=CC([N+]([O-])=O)=CC2=C1N=C(NC3=CC=C(Cl)C(Cl)=C3)NC2=O)NCC=C
Molecular Formula
C18H13Cl2N5O4
Molecular Weight
434.23
References & Citations
[1]Kanauchi Y, et al. Cholinergic anti-inflammatory pathway ameliorates murine experimental Th2-type colitis by suppressing the migration of plasmacytoid dendritic cells[J]. Scientific Reports, 2022, 12 (1) : 54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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