Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Safinamide (Standard)

Safinamide (Standard) is the analytical standard of Safinamide. This product is intended for research and analytical applications. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 µM) [1]. Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 µM) than at resting (IC50=262 µM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al[2][3].

Product Specifications

Product Name Alternative

FCE 26743 (Standard) ; EMD 1195686 (Standard)

UNSPSC

12352005

Target

Monoamine Oxidase; Reference Standards

Type

Reference Standards

Related Pathways

Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/safinamide-standard.html

Smiles

O=C([C@@H](NCC1=CC=C(OCC2=CC(F)=CC=C2)C=C1)C)N

Molecular Formula

C17H19FN2O2

Molecular Weight

302.34

References & Citations

[1]Leonetti F, et al. Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoamine oxidase. J Med Chem, 2007, 50 (20), 4909-4916.|[2]C Caccia, et al.Safinamide: from molecular targets to a new anti-Parkinson drug. Neurology. 2006 Oct 10;67 (7 Suppl 2) :S18-23.|[3]Michele Morari, et al. Safinamide Differentially Modulates In Vivo Glutamate and GABA Release in the Rat Hippocampus and Basal Ganglia.J Pharmacol Exp Ther. 2018 Feb;364 (2) :198-206.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-70057R/Safinamide-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-70057R/

Scientific Category

Reference Standards

CAS Number

[133865-89-1]

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FTHL17 CRISPR All-in-one AAV vector set (with saCas9)(Human)
21027151 3x1.0μg DNA

FTHL17 CRISPR All-in-one AAV vector set (with saCas9)(Human)

Ask
View Details
Glypican-3 shRNA Plasmid (m)
sc-40641-SH 20 µg

Glypican-3 shRNA Plasmid (m)

Ask
View Details
Karyopherin β2 (F-6) Alexa Fluor® 546
sc-166127 AF546 200 µg/mL

Karyopherin β2 (F-6) Alexa Fluor® 546

Ask
View Details
Recombinant Human CD7 Protein, His, Yeast-10ug
QP5794-ye-10ug 10ug

Recombinant Human CD7 Protein, His, Yeast-10ug

Ask
View Details
OACA12783-50UL
OACA12783-50UL 50 µL

OACA12783-50UL

Ask
View Details