VH 032 amide-alkylC6-acid
Product Specifications
UNSPSC Description
VH 032 amide-alkylC6-acid ((S,R,S)-AHPC-CO-C6-COOH) is a VH032 analog that acts as a ligand for VHL, recruiting von Hippel-Lindau (VHL) protein. VH 032 amide-alkylC6-acid can be used in the synthesis of PROTACs[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vh-032-amide-alkylc6-acid.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCCCCCC(O)=O)=O)=O)C[C@H](O)C3
Molecular Weight
586.74
References & Citations
[1]Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer, WO2018081530A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-44630/VH-032-amide-alkylC6-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-44630/
Clinical Information
No Development Reported
CAS Number
2172819-75-7
Available Sizes
Curated Selection
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