LX2931
LX2931 is an inhibitor of Sphingosine 1-Phosphate Lyase (S1PL) . LX2931 works by increasing levels of S1P inside and outside the cell. The decrease in S1PL activity leads to a significant increase in S1P content in tissues, especially in lymphoid tissues which may lead to a restricted exodus of lymphocytes from secondary immune tissues, resulting in lymphocytopenic and immunosuppressive effects in the peripheral circulation. LX2931 can be used in research for the treatment of autoimmune diseases, especially rheumatoid arthritis[1].
Product Specifications
CAS Number
948840-25-3
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Others
Assay Protocol
https://www.medchemexpress.com/lx2931.html
Purity
99.9
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
OC[C@@H](O)[C@@H](O)[C@@H](C1=CN=C(/C(C)=N/O)N1)O
Molecular Formula
C9H15N3O5
Molecular Weight
245.23
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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